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Crystal structures of HER3 extracellular domain 4 in complex with the designed ankyrin-repeat protein D5
The members of the human epidermal growth factor receptor (HER) family are among the most intensely studied oncological targets. HER3 (ErbB3), which had long been neglected, has emerged as a key oncogene, regulating the activity of other receptors and being involved in progression and tumor escape i...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248824/ https://www.ncbi.nlm.nih.gov/pubmed/34196609 http://dx.doi.org/10.1107/S2053230X21006002 |