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Targeting delivery of simvastatin using ICAM-1 antibody-conjugated nanostructured lipid carriers for acute lung injury therapy

Acute lung injury (ALI) is a critical illness without effective therapeutic modalities currently. Recent studies indicated potential efficacy of statins for ALI, while high-dose statins was suggested to be significant for attenuating inflammation in vivo. Therefore, a lung-targeted drug delivery sys...

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Detalles Bibliográficos
Autores principales: Li, Shu-Juan, Wang, Xiao-Juan, Hu, Jing-Bo, Kang, Xu-Qi, Chen, Li, Xu, Xiao-Ling, Ying, Xiao-Ying, Jiang, Sai-Ping, Du, Yong-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248938/
https://www.ncbi.nlm.nih.gov/pubmed/28165814
http://dx.doi.org/10.1080/10717544.2016.1259369