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A humanized monoclonal antibody against the endothelial chemokine CCL21 for the diagnosis and treatment of inflammatory bowel disease

Chemokines are small proteins that promote leukocyte migration during development, infection, and inflammation. We and others isolated the unique chemokine CCL21, a potent chemo-attractant for naïve T-cells, naïve B-cells, and immature dendritic cells. CCL21 has a 37 amino acid carboxy terminal exte...

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Detalles Bibliográficos
Autores principales: Capitano, Maegan L., Jaiswal, Aruna, Broxmeyer, Hal E., Pride, Yilianys, Glover, Sarah, Amlashi, Fatemah G., Kirby, Austin, Srinivasan, Gayathri, Williamson, Elizabeth A., Mais, Daniel, Hromas, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248966/
https://www.ncbi.nlm.nih.gov/pubmed/34197491
http://dx.doi.org/10.1371/journal.pone.0252805