Hepatoenteric recycling is a new disposition mechanism for orally administered phenolic drugs and phytochemicals in rats

Many orally administered phenolic drugs undergo enterohepatic recycling (EHR), presumably mediated by the hepatic phase II enzymes. However, the disposition of extrahepatically generated phase II metabolites is unclear. This paper aims to determine the new roles of liver and intestine in the disposi...

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Detalles Bibliográficos
Autores principales: Tu, Yifan, Wang, Lu, Rong, Yi, Tam, Vincent, Yin, Taijun, Gao, Song, Singh, Rashim, Hu, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248983/
https://www.ncbi.nlm.nih.gov/pubmed/34196607
http://dx.doi.org/10.7554/eLife.58820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248983/
https://www.ncbi.nlm.nih.gov/pubmed/34196607
http://dx.doi.org/10.7554/eLife.58820

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