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Hepatoenteric recycling is a new disposition mechanism for orally administered phenolic drugs and phytochemicals in rats
Many orally administered phenolic drugs undergo enterohepatic recycling (EHR), presumably mediated by the hepatic phase II enzymes. However, the disposition of extrahepatically generated phase II metabolites is unclear. This paper aims to determine the new roles of liver and intestine in the disposi...
Autores principales: | Tu, Yifan, Wang, Lu, Rong, Yi, Tam, Vincent, Yin, Taijun, Gao, Song, Singh, Rashim, Hu, Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248983/ https://www.ncbi.nlm.nih.gov/pubmed/34196607 http://dx.doi.org/10.7554/eLife.58820 |
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