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A novel mitochondrial Kv1.3–caveolin axis controls cell survival and apoptosis

The voltage-gated potassium channel Kv1.3 plays an apparent dual physiological role by participating in activation and proliferation of leukocytes as well as promoting apoptosis in several types of tumor cells. Therefore, Kv1.3 is considered a potential pharmacological target for immunodeficiency an...

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Detalles Bibliográficos
Autores principales: Capera, Jesusa, Pérez-Verdaguer, Mireia, Peruzzo, Roberta, Navarro-Pérez, María, Martínez-Pinna, Juan, Alberola-Die, Armando, Morales, Andrés, Leanza, Luigi, Szabó, Ildiko, Felipe, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248986/
https://www.ncbi.nlm.nih.gov/pubmed/34196606
http://dx.doi.org/10.7554/eLife.69099