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Cryptotanshinone Prevents the Binding of S6K1 to mTOR/Raptor Leading to the Suppression of mTORC1-S6K1 Signaling Activity and Neoplastic Cell Transformation

Cryptotanshinone is known for its inhibitory activity against tumorigenesis in various human cancer cells. However, exact mechanisms underlying the anticancer effects of cryptotanshinone are not fully elucidated. Here, we propose a plausible molecular mechanism, wherein cryptotanshinone represses ra...

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Detalles Bibliográficos
Autores principales: Jeoung, Nam Ho, Jeong, Ji Yun, Kang, Bong Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Cancer Prevention 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249204/
https://www.ncbi.nlm.nih.gov/pubmed/34258253
http://dx.doi.org/10.15430/JCP.2021.26.2.145