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The Dickkopf1 and FOXM1 positive feedback loop promotes tumor growth in pancreatic and esophageal cancers

Dickkopf1 (DKK1) is overexpressed in various cancers and promotes cancer cell proliferation by binding to cytoskeleton-associated protein 4 (CKAP4). However, the mechanisms underlying DKK1 expression are poorly understood. RNA sequence analysis revealed that expression of the transcription factor fo...

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Detalles Bibliográficos
Autores principales: Kimura, Hirokazu, Sada, Ryota, Takada, Naoki, Harada, Akikazu, Doki, Yuichiro, Eguchi, Hidetoshi, Yamamoto, Hideki, Kikuchi, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249240/
https://www.ncbi.nlm.nih.gov/pubmed/34117362
http://dx.doi.org/10.1038/s41388-021-01860-z