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The Dickkopf1 and FOXM1 positive feedback loop promotes tumor growth in pancreatic and esophageal cancers
Dickkopf1 (DKK1) is overexpressed in various cancers and promotes cancer cell proliferation by binding to cytoskeleton-associated protein 4 (CKAP4). However, the mechanisms underlying DKK1 expression are poorly understood. RNA sequence analysis revealed that expression of the transcription factor fo...
Autores principales: | Kimura, Hirokazu, Sada, Ryota, Takada, Naoki, Harada, Akikazu, Doki, Yuichiro, Eguchi, Hidetoshi, Yamamoto, Hideki, Kikuchi, Akira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249240/ https://www.ncbi.nlm.nih.gov/pubmed/34117362 http://dx.doi.org/10.1038/s41388-021-01860-z |
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