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Thymopoiesis, Alterations in Dendritic Cells and Tregs, and Reduced T Cell Activation in Successful Extracorporeal Photopheresis Treatment of GVHD

Acute graft-versus-host disease (aGVHD) is a significant complication of allogeneic hematopoietic stem cell transplant (HSCT) and negatively affects T cell reconstitution. Extracorporeal photopheresis (ECP) reduces aGVHD, but the mechanisms remain incompletely understood. Our objective was to examin...

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Detalles Bibliográficos
Autores principales: Flinn, Aisling M., Ehrlich, Anna, Roberts, Catherine, Wang, Xiao Nong, Chou, Janet, Gennery, Andrew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249294/
https://www.ncbi.nlm.nih.gov/pubmed/33651234
http://dx.doi.org/10.1007/s10875-021-00991-y