A Model-Informed Method for the Purpose of Precision Dosing of Isoniazid in Pulmonary Tuberculosis

BACKGROUND AND OBJECTIVE: This study aimed to develop and evaluate a population pharmacokinetic model and limited sampling strategy for isoniazid to be used in model-based therapeutic drug monitoring. METHODS: A population pharmacokinetic model was developed based on isoniazid and acetyl-isoniazid p...

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Detalles Bibliográficos
Autores principales: van Beek, Stijn W., ter Heine, Rob, Alffenaar, Jan-Willem C., Magis-Escurra, Cecile, Aarnoutse, Rob E., Svensson, Elin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249295/
https://www.ncbi.nlm.nih.gov/pubmed/33615419
http://dx.doi.org/10.1007/s40262-020-00971-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249295/
https://www.ncbi.nlm.nih.gov/pubmed/33615419
http://dx.doi.org/10.1007/s40262-020-00971-2

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