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A Bayesian approach to extracting free-energy profiles from cryo-electron microscopy experiments

Cryo-electron microscopy (cryo-EM) extracts single-particle density projections of individual biomolecules. Although cryo-EM is widely used for 3D reconstruction, due to its single-particle nature it has the potential to provide information about a biomolecule’s conformational variability and underl...

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Detalles Bibliográficos
Autores principales: Giraldo-Barreto, Julian, Ortiz, Sebastian, Thiede, Erik H., Palacio-Rodriguez, Karen, Carpenter, Bob, Barnett, Alex H., Cossio, Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249403/
https://www.ncbi.nlm.nih.gov/pubmed/34211017
http://dx.doi.org/10.1038/s41598-021-92621-1