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A Bayesian approach to extracting free-energy profiles from cryo-electron microscopy experiments
Cryo-electron microscopy (cryo-EM) extracts single-particle density projections of individual biomolecules. Although cryo-EM is widely used for 3D reconstruction, due to its single-particle nature it has the potential to provide information about a biomolecule’s conformational variability and underl...
Autores principales: | Giraldo-Barreto, Julian, Ortiz, Sebastian, Thiede, Erik H., Palacio-Rodriguez, Karen, Carpenter, Bob, Barnett, Alex H., Cossio, Pilar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249403/ https://www.ncbi.nlm.nih.gov/pubmed/34211017 http://dx.doi.org/10.1038/s41598-021-92621-1 |
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