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Spatial distribution of B cells and lymphocyte clusters as a predictor of triple-negative breast cancer outcome

While tumor infiltration by CD8(+) T cells is now widely accepted to predict outcomes, the clinical significance of intratumoral B cells is less clear. We hypothesized that spatial distribution rather than density of B cells within tumors may provide prognostic significance. We developed statistical...

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Detalles Bibliográficos
Autores principales: Wortman, Juliana C., He, Ting-Fang, Solomon, Shawn, Zhang, Robert Z., Rosario, Anthony, Wang, Roger, Tu, Travis Y., Schmolze, Daniel, Yuan, Yuan, Yost, Susan E., Li, Xuefei, Levine, Herbert, Atwal, Gurinder, Lee, Peter P., Yu, Clare C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249408/
https://www.ncbi.nlm.nih.gov/pubmed/34210991
http://dx.doi.org/10.1038/s41523-021-00291-z