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Clonal hematopoiesis and its emerging effects on cellular therapies

The accumulation of somatic mutations in hematopoietic stem cells during aging, leading to clonal expansion, is linked to a higher risk of cardiovascular mortality and hematologic malignancies. Clinically, clonal hematopoiesis is associated with a pro-inflammatory phenotype of hematopoietic cells an...

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Detalles Bibliográficos
Autores principales: von Bonin, Malte, Jambor, Helena Klara, Teipel, Raphael, Stölzel, Friedrich, Thiede, Christian, Damm, Frederik, Kroschinsky, Frank, Schetelig, Johannes, Chavakis, Triantafyllos, Bornhäuser, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249428/
https://www.ncbi.nlm.nih.gov/pubmed/34215849
http://dx.doi.org/10.1038/s41375-021-01337-8