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Complex effects of macrolide venturicidins on bacterial F-ATPases likely contribute to their action as antibiotic adjuvants

Bacterial energy metabolism is now recognized as a critical factor for the efficacy of antibiotics. The F-type ATPase/ATP synthase (F(O)F(1)) is a central player in cellular bioenergetics of bacteria and eukaryotes, and its potential as a selective antibiotic target has been confirmed by the success...

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Detalles Bibliográficos
Autores principales: Milgrom, Yakov M., Duncan, Thomas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249445/
https://www.ncbi.nlm.nih.gov/pubmed/34211053
http://dx.doi.org/10.1038/s41598-021-93098-8