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An alternative pathway for membrane protein biogenesis at the endoplasmic reticulum

The heterotrimeric Sec61 complex is a major site for the biogenesis of transmembrane proteins (TMPs), accepting nascent TMP precursors that are targeted to the endoplasmic reticulum (ER) by the signal recognition particle (SRP). Unlike most single-spanning membrane proteins, the integration of type...

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Detalles Bibliográficos
Autores principales: O’Keefe, Sarah, Zong, Guanghui, Duah, Kwabena B., Andrews, Lauren E., Shi, Wei Q., High, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249459/
https://www.ncbi.nlm.nih.gov/pubmed/34211117
http://dx.doi.org/10.1038/s42003-021-02363-z