Cargando…
An alternative pathway for membrane protein biogenesis at the endoplasmic reticulum
The heterotrimeric Sec61 complex is a major site for the biogenesis of transmembrane proteins (TMPs), accepting nascent TMP precursors that are targeted to the endoplasmic reticulum (ER) by the signal recognition particle (SRP). Unlike most single-spanning membrane proteins, the integration of type...
Autores principales: | O’Keefe, Sarah, Zong, Guanghui, Duah, Kwabena B., Andrews, Lauren E., Shi, Wei Q., High, Stephen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249459/ https://www.ncbi.nlm.nih.gov/pubmed/34211117 http://dx.doi.org/10.1038/s42003-021-02363-z |
Ejemplares similares
-
Ipomoeassin-F inhibits the in vitro biogenesis of the SARS-CoV-2 spike protein and its host cell membrane receptor
por: O’Keefe, Sarah, et al.
Publicado: (2021) -
Ipomoeassin-F inhibits the in vitro biogenesis of the SARS-CoV-2 spike protein and its host cell membrane receptor
por: O'Keefe, Sarah, et al.
Publicado: (2021) -
Ipomoeassin-F disrupts multiple aspects of secretory protein biogenesis
por: Roboti, Peristera, et al.
Publicado: (2021) -
Ring Expansion Leads
to a More Potent Analogue of
Ipomoeassin F
por: Zong, Guanghui, et al.
Publicado: (2020) -
Synthesis, Biological Evaluation and Docking Studies of Ring-Opened Analogues of Ipomoeassin F
por: O’Keefe, Sarah, et al.
Publicado: (2022)