Genetic dissection identifies Necdin as a driver gene in a mouse model of paternal 15q duplications

Maternally inherited duplication of chromosome 15q11-q13 (Dup15q) is a pathogenic copy number variation (CNV) associated with autism spectrum disorder (ASD). Recently, paternally derived duplication has also been shown to contribute to the development of ASD. The molecular mechanism underlying pater...

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Detalles Bibliográficos
Autores principales: Tamada, Kota, Fukumoto, Keita, Toya, Tsuyoshi, Nakai, Nobuhiro, Awasthi, Janak R., Tanaka, Shinji, Okabe, Shigeo, Spitz, François, Saitow, Fumihito, Suzuki, Hidenori, Takumi, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249516/
https://www.ncbi.nlm.nih.gov/pubmed/34210967
http://dx.doi.org/10.1038/s41467-021-24359-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249516/
https://www.ncbi.nlm.nih.gov/pubmed/34210967
http://dx.doi.org/10.1038/s41467-021-24359-3

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