Aggregation is a Context-Dependent Constraint on Protein Evolution

Solubility is a requirement for many cellular processes. Loss of solubility and aggregation can lead to the partial or complete abrogation of protein function. Thus, understanding the relationship between protein evolution and aggregation is an important goal. Here, we analysed two deep mutational s...

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Detalles Bibliográficos
Autores principales: Monti, Michele, Armaos, Alexandros, Fantini, Marco, Pastore, Annalisa, Tartaglia, Gian Gaetano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249573/
https://www.ncbi.nlm.nih.gov/pubmed/34222334
http://dx.doi.org/10.3389/fmolb.2021.678115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249573/
https://www.ncbi.nlm.nih.gov/pubmed/34222334
http://dx.doi.org/10.3389/fmolb.2021.678115

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