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Angle change of the A-domain in a single SERCA1a molecule detected by defocused orientation imaging
The sarcoendoplasmic reticulum Ca(2+)-ATPase (SERCA) transports Ca(2+) ions across the membrane coupled with ATP hydrolysis. Crystal structures of ligand-stabilized molecules indicate that the movement of actuator (A) domain plays a crucial role in Ca(2+) translocation. However, the actual structura...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249593/ https://www.ncbi.nlm.nih.gov/pubmed/34211016 http://dx.doi.org/10.1038/s41598-021-92986-3 |