Optical tissue clearing and machine learning can precisely characterize extravasation and blood vessel architecture in brain tumors

Precise methods for quantifying drug accumulation in brain tissue are currently very limited, challenging the development of new therapeutics for brain disorders. Transcardial perfusion is instrumental for removing the intravascular fraction of an injected compound, thereby allowing for ex vivo asse...

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Detalles Bibliográficos
Autores principales: Kostrikov, Serhii, Johnsen, Kasper B., Braunstein, Thomas H., Gudbergsson, Johann M., Fliedner, Frederikke P., Obara, Elisabeth A. A., Hamerlik, Petra, Hansen, Anders E., Kjaer, Andreas, Hempel, Casper, Andresen, Thomas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249617/
https://www.ncbi.nlm.nih.gov/pubmed/34211069
http://dx.doi.org/10.1038/s42003-021-02275-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249617/
https://www.ncbi.nlm.nih.gov/pubmed/34211069
http://dx.doi.org/10.1038/s42003-021-02275-y

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