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Optical tissue clearing and machine learning can precisely characterize extravasation and blood vessel architecture in brain tumors
Precise methods for quantifying drug accumulation in brain tissue are currently very limited, challenging the development of new therapeutics for brain disorders. Transcardial perfusion is instrumental for removing the intravascular fraction of an injected compound, thereby allowing for ex vivo asse...
Autores principales: | Kostrikov, Serhii, Johnsen, Kasper B., Braunstein, Thomas H., Gudbergsson, Johann M., Fliedner, Frederikke P., Obara, Elisabeth A. A., Hamerlik, Petra, Hansen, Anders E., Kjaer, Andreas, Hempel, Casper, Andresen, Thomas L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249617/ https://www.ncbi.nlm.nih.gov/pubmed/34211069 http://dx.doi.org/10.1038/s42003-021-02275-y |
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