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Visualization and modeling of inhibition of IL-1β and TNF-α mRNA transcription at the single-cell level

IL-1β and TNF-α are canonical immune response mediators that play key regulatory roles in a wide range of inflammatory responses to both chronic and acute conditions. Here we employ an automated microscopy platform for the analysis of messenger RNA (mRNA) expression of IL-1β and TNF-α at the single-...

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Detalles Bibliográficos
Autores principales: Kalb, Daniel, Vo, Huy D., Adikari, Samantha, Hong-Geller, Elizabeth, Munsky, Brian, Werner, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249620/
https://www.ncbi.nlm.nih.gov/pubmed/34211022
http://dx.doi.org/10.1038/s41598-021-92846-0