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Deletion of the diabetes candidate gene Slc16a13 in mice attenuates diet-induced ectopic lipid accumulation and insulin resistance

Genome-wide association studies have identified SLC16A13 as a novel susceptibility gene for type 2 diabetes. The SLC16A13 gene encodes SLC16A13/MCT13, a member of the solute carrier 16 family of monocarboxylate transporters. Despite its potential importance to diabetes development, the physiological...

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Detalles Bibliográficos
Autores principales: Schumann, Tina, König, Jörg, von Loeffelholz, Christian, Vatner, Daniel F., Zhang, Dongyan, Perry, Rachel J., Bernier, Michel, Chami, Jason, Henke, Christine, Kurzbach, Anica, El-Agroudy, Nermeen N., Willmes, Diana M., Pesta, Dominik, de Cabo, Rafael, O´Sullivan, John F., Simon, Eric, Shulman, Gerald I., Hamilton, Bradford S., Birkenfeld, Andreas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249653/
https://www.ncbi.nlm.nih.gov/pubmed/34211098
http://dx.doi.org/10.1038/s42003-021-02279-8