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The origin and radiation of the phosphoprotein phosphatase (PPP) enzymes of Eukaryotes

Phosphoprotein phosphatase (PPP) enzymes are ubiquitous proteins involved in cellular signaling pathways and other functions. Here we have traced the origin of the PPP sequences of Eukaryotes and their radiation. Using a bacterial PPP Hidden Markov Model (HMM) we uncovered “BacterialPPP-Like” sequen...

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Detalles Bibliográficos
Autores principales: Kerk, David, Mattice, Jordan F., Valdés-Tresanco, Mario E., Noskov, Sergei Yu, Ng, Kenneth K.-S., Moorhead, Greg B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249667/
https://www.ncbi.nlm.nih.gov/pubmed/34211082
http://dx.doi.org/10.1038/s41598-021-93206-8