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Display of the human mucinome with defined O-glycans by gene engineered cells

Mucins are a large family of heavily O-glycosylated proteins that cover all mucosal surfaces and constitute the major macromolecules in most body fluids. Mucins are primarily defined by their variable tandem repeat (TR) domains that are densely decorated with different O-glycan structures in distinc...

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Detalles Bibliográficos
Autores principales: Nason, Rebecca, Büll, Christian, Konstantinidi, Andriana, Sun, Lingbo, Ye, Zilu, Halim, Adnan, Du, Wenjuan, Sørensen, Daniel M., Durbesson, Fabien, Furukawa, Sanae, Mandel, Ulla, Joshi, Hiren J., Dworkin, Leo Alexander, Hansen, Lars, David, Leonor, Iverson, Tina M., Bensing, Barbara A., Sullam, Paul M., Varki, Ajit, Vries, Erik de, de Haan, Cornelis A. M., Vincentelli, Renaud, Henrissat, Bernard, Vakhrushev, Sergey Y., Clausen, Henrik, Narimatsu, Yoshiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249670/
https://www.ncbi.nlm.nih.gov/pubmed/34210959
http://dx.doi.org/10.1038/s41467-021-24366-4