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Impact of SARS-CoV-2 variants on the total CD4(+) and CD8(+) T cell reactivity in infected or vaccinated individuals

The emergence of SARS-CoV-2 variants with evidence of antibody escape highlight the importance of addressing whether the total CD4(+) and CD8(+) T cell recognition is also affected. Here, we compare SARS-CoV-2-specific CD4(+) and CD8(+) T cells against the B.1.1.7, B.1.351, P.1, and CAL.20C lineages...

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Detalles Bibliográficos
Autores principales: Tarke, Alison, Sidney, John, Methot, Nils, Yu, Esther Dawen, Zhang, Yun, Dan, Jennifer M., Goodwin, Benjamin, Rubiro, Paul, Sutherland, Aaron, Wang, Eric, Frazier, April, Ramirez, Sydney I., Rawlings, Stephen A., Smith, Davey M., da Silva Antunes, Ricardo, Peters, Bjoern, Scheuermann, Richard H., Weiskopf, Daniela, Crotty, Shane, Grifoni, Alba, Sette, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249675/
https://www.ncbi.nlm.nih.gov/pubmed/34230917
http://dx.doi.org/10.1016/j.xcrm.2021.100355