Effects of Ribosomal Protein S10 Flexible Loop Mutations on Tetracycline and Tigecycline Susceptibility of Escherichia coli

Tigecycline is a tetracycline derivative that is being used as an antibiotic of last resort. Both tigecycline and tetracycline bind to the small (30S) ribosomal subunit and inhibit translation. Target mutations leading to resistance to these antibiotics have been identified both in the 16S ribosomal...

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Detalles Bibliográficos
Autores principales: Izghirean, Norbert, Waidacher, Claudia, Kittinger, Clemens, Chyba, Miriam, Koraimann, Günther, Pertschy, Brigitte, Zarfel, Gernot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249722/
https://www.ncbi.nlm.nih.gov/pubmed/34220749
http://dx.doi.org/10.3389/fmicb.2021.663835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249722/
https://www.ncbi.nlm.nih.gov/pubmed/34220749
http://dx.doi.org/10.3389/fmicb.2021.663835

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