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Analysis of SARS-CoV-2 nucleocapsid phosphoprotein N variations in the binding site to human 14-3-3 proteins

The SARS-CoV-2 N protein binds several cell host proteins including 14-3-3γ, a well-characterized regulatory protein. However, the biological function of this interaction is not completely understood. We analyzed the variability of ∼90 000 sequences of the SARS-CoV-2 N protein, particularly, its mut...

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Detalles Bibliográficos
Autores principales: Del Veliz, Samanta, Rivera, Lautaro, Bustos, Diego M., Uhart, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249750/
https://www.ncbi.nlm.nih.gov/pubmed/34246830
http://dx.doi.org/10.1016/j.bbrc.2021.06.100