Poly (ADP-ribose) Interacts With Phosphorylated α-Synuclein in Post Mortem PD Samples

Poly (ADP-ribose) (PAR) is a negatively charged polymer that is biosynthesized by Poly (ADP-ribose) Polymerase-1 (PARP-1) and regulates various cellular processes. Alpha-synuclein (αSyn) is an intrinsically disordered protein (IDP) that has been directly implicated with driving the onset and progres...

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Detalles Bibliográficos
Autores principales: Puentes, Laura N., Lengyel-Zhand, Zsofia, Lee, Ji Youn, Hsieh, Chia-Ju, Schneider, Mark E., Edwards, Kimberly J., Luk, Kelvin C., Lee, Virginia M.-Y., Trojanowski, John Q., Mach, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249773/
https://www.ncbi.nlm.nih.gov/pubmed/34220490
http://dx.doi.org/10.3389/fnagi.2021.704041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249773/
https://www.ncbi.nlm.nih.gov/pubmed/34220490
http://dx.doi.org/10.3389/fnagi.2021.704041

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