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Mass cytometry and transcriptomic profiling reveal body‐wide pathology induced by Loxl1 deficiency

OBJECTIVE: The loss of LOXL1 expression reportedly leads to the prolapse of pelvic organs or to exfoliation syndrome glaucoma. Increasing evidence suggests that LOXL1 deficiency is associated with the pathogenesis of several other diseases. However, the characterization of the systemic functions of...

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Detalles Bibliográficos
Autores principales: Li, Yu, Wu, Bingbing, An, Chengrui, Jiang, Deming, Gong, Lin, Liu, Yanshan, Liu, Yixiao, Li, Jun, Ouyang, Hongwei, Zou, XiaoHui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249785/
https://www.ncbi.nlm.nih.gov/pubmed/34105806
http://dx.doi.org/10.1111/cpr.13077