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Cathepsin K deficiency promotes alveolar bone regeneration by promoting jaw bone marrow mesenchymal stem cells proliferation and differentiation via glycolysis pathway

OBJECTIVES: To clarify the possible role and mechanism of Cathepsin K (CTSK) in alveolar bone regeneration mediated by jaw bone marrow mesenchymal stem cells (JBMMSC). MATERIALS AND METHODS: Tooth extraction models of Ctsk knockout mice (Ctsk (‐/‐)) and their wildtype (WT) littermates were used to i...

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Detalles Bibliográficos
Autores principales: Zhang, Wuyang, Dong, Zhiwei, Li, Dengke, Li, Bei, Liu, Yuan, Zheng, Xueni, Liu, Hui, Zhou, Hongzhi, Hu, Kaijin, Xue, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249792/
https://www.ncbi.nlm.nih.gov/pubmed/34053135
http://dx.doi.org/10.1111/cpr.13058