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Integration of Engineered “Spark-Cell” Spheroids for Optical Pacing of Cardiac Tissue
Optogenetic methods for pacing of cardiac tissue can be realized by direct genetic modification of the cardiomyocytes to express light-sensitive actuators, such as channelrhodopsin-2, ChR2, or by introduction of light-sensitized non-myocytes that couple to the cardiac cells and yield responsiveness...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249938/ https://www.ncbi.nlm.nih.gov/pubmed/34222210 http://dx.doi.org/10.3389/fbioe.2021.658594 |