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Integration of Engineered “Spark-Cell” Spheroids for Optical Pacing of Cardiac Tissue

Optogenetic methods for pacing of cardiac tissue can be realized by direct genetic modification of the cardiomyocytes to express light-sensitive actuators, such as channelrhodopsin-2, ChR2, or by introduction of light-sensitized non-myocytes that couple to the cardiac cells and yield responsiveness...

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Detalles Bibliográficos
Autores principales: Chua, Christianne J., Han, Julie L., Li, Weizhen, Liu, Wei, Entcheva, Emilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249938/
https://www.ncbi.nlm.nih.gov/pubmed/34222210
http://dx.doi.org/10.3389/fbioe.2021.658594