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CAR-T Cell Therapy: Mechanism, Management, and Mitigation of Inflammatory Toxicities

Engineered T cell therapies such as chimeric antigen receptor (CAR) expressing T cells (CAR-T cells) have great potential to treat many human diseases; however, inflammatory toxicities associated with these therapies present safety risks and can greatly limit its widespread use. This article briefly...

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Detalles Bibliográficos
Autores principales: Fischer, Joseph W., Bhattarai, Nirjal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8250150/
https://www.ncbi.nlm.nih.gov/pubmed/34220853
http://dx.doi.org/10.3389/fimmu.2021.693016