Linking Chromosomal Silencing With Xist Expression From Autosomal Integrated Transgenes

Xist is the master regulator of X-Chromosome Inactivation (XCI), the mammalian dosage compensation mechanism that silences one of the two X chromosomes in a female cell. XCI is established during early embryonic development. Xist transgene (Tg) integrated into an autosome can induce transcriptional...

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Detalles Bibliográficos
Autores principales: Naciri, Ikrame, Lin, Benjamin, Webb, Chiu-Ho, Jiang, Shan, Carmona, Sarah, Liu, Wenzhu, Mortazavi, Ali, Sun, Sha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8250153/
https://www.ncbi.nlm.nih.gov/pubmed/34222260
http://dx.doi.org/10.3389/fcell.2021.693154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8250153/
https://www.ncbi.nlm.nih.gov/pubmed/34222260
http://dx.doi.org/10.3389/fcell.2021.693154

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