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Enrichment of CCR6(+)CD8(+) T cells and CCL20 in the lungs of mechanically ventilated patients with COVID‐19

Despite high levels of CXCR3 ligands in mechanically ventilated COVID‐19 patients, BALF CD8 T cells were not enriched in CXCR3(+) cells but rather CCR6(+), likely due to high CCL20 levels in BALF, and had very high PD‐1 expression. In mechanically ventilated, but not ward, patients Th‐1 immunity is...

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Detalles Bibliográficos
Autores principales: Saris, Anno, Reijnders, Tom D.Y., Reijm, Martine, Hollander, Jolien C., de Buck, Kim, Schuurman, Alex R., Duitman, JanWillem, Heunks, Leo, Aman, Jurjan, Bogaard, Harm Jan, Nossent, Esther J., van der Poll, Tom, Bontkes, Hetty J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8250259/
https://www.ncbi.nlm.nih.gov/pubmed/33768543
http://dx.doi.org/10.1002/eji.202049046