Combining selective inhibitors of nuclear export (SINEs) with chimeric antigen receptor (CAR) T cells for CD19-positive malignancies

Chimeric antigen receptor (CAR) T cells directed against CD19 (CD19.CAR T cells) have yielded impressive clinical responses in the treatment of patients with lymphoid malignancies. However, resistance and/or relapse can limit treatment outcome. Risk of tumor escape can be reduced by combining treatm...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Sanmei, Sellner, Leopold, Wang, Lei, Sauer, Tim, Neuber, Brigitte, Gong, Wenjie, Stock, Sophia, Ni, Ming, Yao, Hao, Kleist, Christian, Schmitt, Anita, Müller-Tidow, Carsten, Schmitt, Michael, Schubert, Maria-Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8250584/
https://www.ncbi.nlm.nih.gov/pubmed/34165175
http://dx.doi.org/10.3892/or.2021.8121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8250584/
https://www.ncbi.nlm.nih.gov/pubmed/34165175
http://dx.doi.org/10.3892/or.2021.8121

Ejemplares similares