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Silibinin as potential tool against SARS‐Cov‐2: In silico spike receptor‐binding domain and main protease molecular docking analysis, and in vitro endothelial protective effects

The spread of SARS‐CoV‐2, along with the lack of targeted medicaments, encouraged research of existing drugs for repurposing. The rapid response to SARS‐CoV‐2 infection comprises a complex interaction of cytokine storm, endothelial dysfunction, inflammation, and pathologic coagulation. Thus, active...

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Detalles Bibliográficos
Autores principales: Speciale, Antonio, Muscarà, Claudia, Molonia, Maria Sofia, Cimino, Francesco, Saija, Antonella, Giofrè, Salvatore Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251480/
https://www.ncbi.nlm.nih.gov/pubmed/33822421
http://dx.doi.org/10.1002/ptr.7107