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Relationship Between Oral Semaglutide Tablet Erosion and Pharmacokinetics: A Pharmacoscintigraphic Study

Semaglutide, a glucagon‐like peptide‐1 (GLP‐1) analogue, has been coformulated in a tablet with the absorption enhancer, sodium N‐(8‐[2‐hydroxybenzoyl] amino) caprylate (SNAC). We investigated tablet erosion and the pharmacokinetics of oral semaglutide administered with 2 different water volumes and...

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Detalles Bibliográficos
Autores principales: Bækdal, Tine A., Donsmark, Morten, Hartoft‐Nielsen, Marie‐Louise, Søndergaard, Flemming L., Connor, Alyson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251533/
https://www.ncbi.nlm.nih.gov/pubmed/33750044
http://dx.doi.org/10.1002/cpdd.938