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Mutations in Profilin 1 Cause Early‐Onset Paget's Disease of Bone With Giant Cell Tumors
Paget's disease of bone (PDB) is a late‐onset chronic progressive bone disease characterized by abnormal activation of osteoclasts that results in bone pain, deformities, and fractures. PDB is very rare in Asia. A subset of PDB patients have early onset and can develop malignant giant cell tumo...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251538/ https://www.ncbi.nlm.nih.gov/pubmed/33599011 http://dx.doi.org/10.1002/jbmr.4275 |