Insights into the etiology and physiopathology of MODY5/HNF1B pancreatic phenotype with a mouse model of the human disease

Maturity‐onset diabetes of the young type 5 (MODY5) is due to heterozygous mutations or deletion of HNF1B. No mouse models are currently available to recapitulate the human MODY5 disease. Here, we investigate the pancreatic phenotype of a unique MODY5 mouse model generated by heterozygous insertion...

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Detalles Bibliográficos
Autores principales: Quilichini, Evans, Fabre, Mélanie, Nord, Christoffer, Dirami, Thassadite, Le Marec, Axelle, Cereghini, Silvia, Pasek, Raymond C, Gannon, Maureen, Ahlgren, Ulf, Haumaitre, Cécile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2021
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251562/
https://www.ncbi.nlm.nih.gov/pubmed/33527355
http://dx.doi.org/10.1002/path.5629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251562/
https://www.ncbi.nlm.nih.gov/pubmed/33527355
http://dx.doi.org/10.1002/path.5629

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