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Insights into the etiology and physiopathology of MODY5/HNF1B pancreatic phenotype with a mouse model of the human disease
Maturity‐onset diabetes of the young type 5 (MODY5) is due to heterozygous mutations or deletion of HNF1B. No mouse models are currently available to recapitulate the human MODY5 disease. Here, we investigate the pancreatic phenotype of a unique MODY5 mouse model generated by heterozygous insertion...
Autores principales: | Quilichini, Evans, Fabre, Mélanie, Nord, Christoffer, Dirami, Thassadite, Le Marec, Axelle, Cereghini, Silvia, Pasek, Raymond C, Gannon, Maureen, Ahlgren, Ulf, Haumaitre, Cécile |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251562/ https://www.ncbi.nlm.nih.gov/pubmed/33527355 http://dx.doi.org/10.1002/path.5629 |
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