A Phase 1 Study to Investigate the Effects of Cortexolone 17α‐Propionate, Also Known as Clascoterone, on the QT Interval Using the Meal Effect to Demonstrate ECG Assay Sensitivity

Cortexolone 17α‐propionate, also known as clascoterone, is a potent androgen receptor inhibitor intended for the topical treatment of skin diseases associated with androgenic pathway alterations. In nonclinical studies, cortexolone 17α‐propionate was found to have a weak inhibitory effect on human E...

Descripción completa

Detalles Bibliográficos
Autores principales: Täubel, Jörg, Mazzetti, Alessandro, Ferber, Georg, Burch, William, Fernandes, Sara, Patel, Avani, Spencer, Christopher S., Freier, Anne, Graff, Claus, Kanters, Jørgen K., Camm, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251570/
https://www.ncbi.nlm.nih.gov/pubmed/33942574
http://dx.doi.org/10.1002/cpdd.935

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251570/
https://www.ncbi.nlm.nih.gov/pubmed/33942574
http://dx.doi.org/10.1002/cpdd.935

Ejemplares similares