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Intracellular amyloid hypothesis for ultra‐early phase pathology of Alzheimer's disease

Using a new marker of necrosis, pSer46‐MARCKS, which was identified by comprehensive phosphoproteome analysis as a phosphoprotein changed before appearance of extracellular amyloid aggregation, we discovered that neuronal necrosis occurs much earlier in Alzheimer's disease pathology than previo...

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Detalles Bibliográficos
Autor principal: Okazawa, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251586/
https://www.ncbi.nlm.nih.gov/pubmed/33876503
http://dx.doi.org/10.1111/neup.12738