Cargando…
Intracellular amyloid hypothesis for ultra‐early phase pathology of Alzheimer's disease
Using a new marker of necrosis, pSer46‐MARCKS, which was identified by comprehensive phosphoproteome analysis as a phosphoprotein changed before appearance of extracellular amyloid aggregation, we discovered that neuronal necrosis occurs much earlier in Alzheimer's disease pathology than previo...
Autor principal: | |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons Australia, Ltd
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251586/ https://www.ncbi.nlm.nih.gov/pubmed/33876503 http://dx.doi.org/10.1111/neup.12738 |