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Hyperpolarized (13)C Magnetic Resonance Imaging of Fumarate Metabolism by Parahydrogen‐induced Polarization: A Proof‐of‐Concept in vivo Study

Hyperpolarized [1‐(13)C]fumarate is a promising magnetic resonance imaging (MRI) biomarker for cellular necrosis, which plays an important role in various disease and cancerous pathological processes. To demonstrate the feasibility of MRI of [1‐(13)C]fumarate metabolism using parahydrogen‐induced po...

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Detalles Bibliográficos
Autores principales: Stewart, Neil J., Nakano, Hitomi, Sugai, Shuto, Tomohiro, Mitsushi, Kase, Yuki, Uchio, Yoshiki, Yamaguchi, Toru, Matsuo, Yujirou, Naganuma, Tatsuya, Takeda, Norihiko, Nishimura, Ikuya, Hirata, Hiroshi, Hashimoto, Takuya, Matsumoto, Shingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251594/
https://www.ncbi.nlm.nih.gov/pubmed/33590933
http://dx.doi.org/10.1002/cphc.202001038