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Light‐Driven gem Hydrogenation: An Orthogonal Entry into “Second‐Generation” Ruthenium Carbene Catalysts for Olefin Metathesis
The newly discovered light‐driven gem hydrogenation of alkynes opens an unconventional yet efficient entry into five‐coordinate Grubbs‐type ruthenium carbene complexes with cis‐disposed chloride ligands. Representatives of this class featuring a chelate substructure formed by an iodo‐substituted ben...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251631/ https://www.ncbi.nlm.nih.gov/pubmed/33871083 http://dx.doi.org/10.1002/chem.202101176 |
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author | Zachmann, Raphael J. Fürstner, Alois |
author_facet | Zachmann, Raphael J. Fürstner, Alois |
author_sort | Zachmann, Raphael J. |
collection | PubMed |
description | The newly discovered light‐driven gem hydrogenation of alkynes opens an unconventional yet efficient entry into five‐coordinate Grubbs‐type ruthenium carbene complexes with cis‐disposed chloride ligands. Representatives of this class featuring a chelate substructure formed by an iodo‐substituted benzylidene unit react with (substituted) 2‐isopropoxystyrene to give prototypical “second‐generation” Grubbs‐Hoveyda complexes for olefin metathesis. The new approach to this venerable catalyst family is safe and versatile as it uses a triple bond rather than phenyldiazomethane as the ultimate carbene source and does not require any sacrificial phosphines. |
format | Online Article Text |
id | pubmed-8251631 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-82516312021-07-06 Light‐Driven gem Hydrogenation: An Orthogonal Entry into “Second‐Generation” Ruthenium Carbene Catalysts for Olefin Metathesis Zachmann, Raphael J. Fürstner, Alois Chemistry Communications The newly discovered light‐driven gem hydrogenation of alkynes opens an unconventional yet efficient entry into five‐coordinate Grubbs‐type ruthenium carbene complexes with cis‐disposed chloride ligands. Representatives of this class featuring a chelate substructure formed by an iodo‐substituted benzylidene unit react with (substituted) 2‐isopropoxystyrene to give prototypical “second‐generation” Grubbs‐Hoveyda complexes for olefin metathesis. The new approach to this venerable catalyst family is safe and versatile as it uses a triple bond rather than phenyldiazomethane as the ultimate carbene source and does not require any sacrificial phosphines. John Wiley and Sons Inc. 2021-05-01 2021-05-17 /pmc/articles/PMC8251631/ /pubmed/33871083 http://dx.doi.org/10.1002/chem.202101176 Text en © 2021 The Authors. Published by Wiley-VCH GmbH https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Communications Zachmann, Raphael J. Fürstner, Alois Light‐Driven gem Hydrogenation: An Orthogonal Entry into “Second‐Generation” Ruthenium Carbene Catalysts for Olefin Metathesis |
title | Light‐Driven gem Hydrogenation: An Orthogonal Entry into “Second‐Generation” Ruthenium Carbene Catalysts for Olefin Metathesis |
title_full | Light‐Driven gem Hydrogenation: An Orthogonal Entry into “Second‐Generation” Ruthenium Carbene Catalysts for Olefin Metathesis |
title_fullStr | Light‐Driven gem Hydrogenation: An Orthogonal Entry into “Second‐Generation” Ruthenium Carbene Catalysts for Olefin Metathesis |
title_full_unstemmed | Light‐Driven gem Hydrogenation: An Orthogonal Entry into “Second‐Generation” Ruthenium Carbene Catalysts for Olefin Metathesis |
title_short | Light‐Driven gem Hydrogenation: An Orthogonal Entry into “Second‐Generation” Ruthenium Carbene Catalysts for Olefin Metathesis |
title_sort | light‐driven gem hydrogenation: an orthogonal entry into “second‐generation” ruthenium carbene catalysts for olefin metathesis |
topic | Communications |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251631/ https://www.ncbi.nlm.nih.gov/pubmed/33871083 http://dx.doi.org/10.1002/chem.202101176 |
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