Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing DNA damage with the CometChip and mutagenesis by Duplex Sequencing

The organotypic human air‐liquid‐interface (ALI) airway tissue model has been used as an in vitro cell culture system for evaluating the toxicity of inhaled substances. ALI airway cultures are highly differentiated, which has made it challenging to evaluate genetic toxicology endpoints. In the curre...

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Detalles Bibliográficos
Autores principales: Wang, Yiying, Mittelstaedt, Roberta A., Wynne, Rebecca, Chen, Ying, Cao, Xuefei, Muskhelishvili, Levan, Davis, Kelly, Robison, Timothy W., Sun, Wei, Schmidt, Elizabeth K., Smith, Thomas H., Norgaard, Zachary K., Valentine, Charles C., Yaplee, Jeffry, Williams, Lindsey N., Salk, Jesse J., Heflich, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251634/
https://www.ncbi.nlm.nih.gov/pubmed/34050964
http://dx.doi.org/10.1002/em.22444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251634/
https://www.ncbi.nlm.nih.gov/pubmed/34050964
http://dx.doi.org/10.1002/em.22444

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