Oxa Analogues of Nexturastat A Demonstrate Improved HDAC6 Selectivity and Superior Antileukaemia Activity

The acetylome is important for maintaining the homeostasis of cells. Abnormal changes can result in the pathogenesis of immunological or neurological diseases, and degeneration can promote the manifestation of cancer. In particular, pharmacological intervention in the acetylome with pan‐histone deac...

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Detalles Bibliográficos
Autores principales: Pflieger, Marc, Sönnichsen, Melf, Horstick‐Muche, Nadine, Yang, Jing, Schliehe‐Diecks, Julian, Schöler, Andrea, Borkhardt, Arndt, Hamacher, Alexandra, Kassack, Matthias U., Hansen, Finn K., Bhatia, Sanil, Kurz, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251746/
https://www.ncbi.nlm.nih.gov/pubmed/33629513
http://dx.doi.org/10.1002/cmdc.202001011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251746/
https://www.ncbi.nlm.nih.gov/pubmed/33629513
http://dx.doi.org/10.1002/cmdc.202001011

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