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ParaHydrogen Polarized Ethyl‐[1‐(13)C]pyruvate in Water, a Key Substrate for Fostering the PHIP‐SAH Approach to Metabolic Imaging
An efficient synthesis of vinyl‐[1‐(13)C]pyruvate has been reported, from which (13)C hyperpolarized (HP) ethyl‐[1‐(13)C]pyruvate has been obtained by means of ParaHydrogen Induced Polarization (PHIP). Due to the intrinsic lability of pyruvate, which leads quickly to degradation of the reaction mixt...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251755/ https://www.ncbi.nlm.nih.gov/pubmed/33720491 http://dx.doi.org/10.1002/cphc.202100062 |