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ParaHydrogen Polarized Ethyl‐[1‐(13)C]pyruvate in Water, a Key Substrate for Fostering the PHIP‐SAH Approach to Metabolic Imaging

An efficient synthesis of vinyl‐[1‐(13)C]pyruvate has been reported, from which (13)C hyperpolarized (HP) ethyl‐[1‐(13)C]pyruvate has been obtained by means of ParaHydrogen Induced Polarization (PHIP). Due to the intrinsic lability of pyruvate, which leads quickly to degradation of the reaction mixt...

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Detalles Bibliográficos
Autores principales: Carrera, Carla, Cavallari, Eleonora, Digilio, Giuseppe, Bondar, Oksana, Aime, Silvio, Reineri, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251755/
https://www.ncbi.nlm.nih.gov/pubmed/33720491
http://dx.doi.org/10.1002/cphc.202100062